Nature

The energy landscape for R-loop formation by the CRISPR–Cas Cascade complex

The alternative text for this image may have been generated using AI. Fig. 3: Long-range R-loop dynamics are governed by the 6 bp periodicity of the crRNA–target strand hybrid. The alternative text ...
Nature

Intertwining roles of R-loops and G-quadruplexes in DNA repair, transcription and genome organization

The alternative text for this image may have been generated using AI. The natural prevalence of R-loops and G4s at telomeres and promoters can facilitate genomic maintenance of these features. At ...
Phys.org

Link between excessive R-loop levels and DNA damage to be a potential cause of disease

There are many ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops. These ...
EurekAlert!

mDRIP-seq: a high-throughput and low-cost method for quantitative R-loop profiling in multiple organisms

This study is achieved by Professor Wei Xu’s research team from Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences. The research team established mDRIP-seq, a ...