Tumor-Infiltrating Lymphocyte Function Predicts Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Oxaliplatin forms part of routine treatment of advanced colorectal cancer; ...

Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents.

Hailin Wang, Meiling Lu, Moon-Shong Tang, Bennett van Houten, J. B. Alexander Ross, Michael Weinfeld, X. Chris Le, Philip C. Hanawalt Proceedings of the National ...

Maintaining the stability of the genome is essential for all organisms, and it is not surprising that damage to DNA has been proposed as an explanation for multiple chronic diseases. 1–5 Conserving a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 4 (Feb. 19, 2002), pp. 1905-1909 (5 pages) DNA-protein crosslinks (DPCs) arise in biological systems as a ...

DNA repair pathways exist to correct molecular damage caused by internal and external factors. However, any damage to these pathways can result in the creation of tumors and specific types of cancers.

The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search ...

Impact of next-generation sequencing (NGS) on the diagnosis of gliomas according to the WHO-2016 and WHO-2021 classification in routine clinical practice. This is an ASCO Meeting Abstract from the ...

CHAPEL HILL – Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact ...